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COXFLAM TAB

COXFLAM TAB
(10)

Composition:

NIMESULIDE-100MG

Group Name:

NSAIDS-ANTIPYRETIC/ANALGESICS

Manufacturer:

LOMUS PHARMACEUTICALS PVT LTD.

Rs 2.79 / TAB
Rs 3.00 7% off

Product Details

NIMESULIDE

MECHANISM OF ACTION : It is a weak inhibitor of PG synthesis and there is some evidence to indicate relative COX-2 selectivity. Antiinflammatory action may be exerted by other mechanisms as well, eg. reduced generation of superoxide by neutrophils, inhibition of PAF synthesis and TNF release, free radical scavanging, inhibition of metalloproteinase activity in cartilage.

USES : It is used primarily for short-lasting painful inflammatory conditions like sports injuries, sinusitis and other ear-nose-threat disorders, dental surgery, bursitis, low backache, dysmenorrhea, postoperative pain, osteoarthritis and for fever.

PHARMACOKINETICS : It is almostly completely absorbed orally, 99% plasma protein bound, extensively metabolized and excreted mainly in urine with a hallife of 2-5 hours.

ADVERSE EFFECTS : 

Gastrointestinal (epigastralgia, heart burn, nausea, loose motions)

Dermatological (rash, pruritis)

Central (somnolence, dizziness)

CONTRAINDICATIONS AND PRECAUTIONS :

Hepatotoxicity, Nephrotoxicity

SOURCE : ESSENTIALS OF MEDIAL PHARMACOLOGY, KD TRIPATHI

Substitutes
AARAM DT-100MG

AARAM DT-100MG 7% off

(25X10S')

Manufacturer: MAGNUS PHARMA-ASTRAL DIVISION

Rs 2.79 / TAB
Rs 3.00
ANIM CD-100MG

ANIM CD-100MG 7% off

(10)

Manufacturer: NEPAL PHARMACEUTICAL LAB LTD.

Rs 2.79 / TAB
Rs 3.00
C-NIM 100MG

C-NIM 100MG 7% off

(25X10'S)

Manufacturer: CHEMIDRUG INDUSTRIES P. LTD.

Rs 2.79 / TAB
Rs 3.00
NIBUCID-100MG

NIBUCID-100MG 7% off

(10)

Manufacturer: CTL PHARMACEUTICALS- PHARMA "A" DIV

Rs 2.79 / TAB
Rs 3.00
NILE TAB.

NILE TAB. 7% off

Manufacturer: S.R. DRUG LAB, NEPAL

Rs 2.79 / TAB.
Rs 3.00
NIMAC TABLET

NIMAC TABLET 7% off

(20X10'S)

Manufacturer: BIOGAIN REMEDIES P. LTD.

Rs 2.79 / TAB
Rs 3.00

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