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FIDIC

FIDIC
(1)

Composition:

FUSIDIC ACID-2% W/W

Group Name:

TOPICAL ANTIBIOTICS

Manufacturer:

QMED FORMULATION PVT.LTD

Rs 69.75 / TUBE.
Rs 75.00 7% off

Product Details

FUSIDIC ACID

An antibiotic isolated from the fermentation broth of Fusidium coccineum. It acts by inhibiting translocation during protein synthesis.

Indication

For the treatment of bacterial infections.

Associated Conditions

Pharmacodynamics

Fusidic acid is a bacteriostatic antibiotic that is often used topically in creams and eyedrops, but may also be given systemically as tablets or injections.

Mechanism of action

Fusidic acid works by interfering with bacterial protein synthesis, specifically by preventing the translocation of the elongation factor G (EF-G) from the ribosome. It also can inhibit chloramphenicol acetyltransferase enzymes.

Absorption

Sodium fusidic acid tablets have a 91% oral bioavailability. Absorption of the film-coated tablets is complete when compared to a solution, however oral absorption is variable. Oral fusidic acid hemihydrate (suspension) achieved a 22.5% bioavailability in pediatric patients following a 20 milligram/kilogram dose.

Volume of distribution

Not Available

Protein binding

97 to 99%

Metabolism

Metabolites include dicarboxylic ester/acid, 3-keto fusidic acid, hydroxy fusidic acid, glucuronide fusidic acid and a glycol metabolite.

SOURCE:DRUGBANK

Substitutes
FUBIOTIC CREAM-15M

FUBIOTIC CREAM-15M 7% off

Manufacturer: CTL PHARMACEUTICALS- PHARMA "A" DIV

Rs 102.30 / TUBE
Rs 110.00

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