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COXFLAM TRANSGEL

COXFLAM TRANSGEL
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Composition:

NIMESULIDE-1%W/W

Group Name:

NSAIDS/ANTI-PYRETICS/ANALGESIC

Manufacturer:

LOMUS PHARMACEUTICALS PVT LTD.

Rs 43.69 / TUBE
Rs 46.98 7% off

Product Details

NIMESULIDE

MECHANISM OF ACTION : It is a weak inhibitor of PG synthesis and there is some evidence to indicate relative COX-2 selectivity. Antiinflammatory action may be exerted by other mechanisms as well, eg. reduced generation of superoxide by neutrophils, inhibition of PAF synthesis and TNF release, free radical scavanging, inhibition of metalloproteinase activity in cartilage.

USES : It is used primarily for short-lasting painful inflammatory conditions like sports injuries, sinusitis and other ear-nose-threat disorders, dental surgery, bursitis, low backache, dysmenorrhea, postoperative pain, osteoarthritis and for fever.

PHARMACOKINETICS : It is almostly completely absorbed orally, 99% plasma protein bound, extensively metabolized and excreted mainly in urine with a hallife of 2-5 hours.

ADVERSE EFFECTS : 

Gastrointestinal (epigastralgia, heart burn, nausea, loose motions)

Dermatological (rash, pruritis)

Central (somnolence, dizziness)

CONTRAINDICATIONS AND PRECAUTIONS :

Hepatotoxicity, Nephrotoxicity

SOURCE : ESSENTIALS OF MEDIAL PHARMACOLOGY, KD TRIPATHI

Substitutes
C-NIMS GEL-30GM

C-NIMS GEL-30GM 7% off

Manufacturer: CHEMIDRUG INDUSTRIES P. LTD.

Rs 93.00 / TUBE
Rs 100.00
NIMS GEL 30GM

NIMS GEL 30GM 7% off

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Manufacturer: ASIAN PHARMACEUTICALS-PHARMA-DIVISION

Rs 93.00 / TUBE
Rs 100.00
NIMULID TRANSGEL-30G.

NIMULID TRANSGEL-30G. 7% off

(1)

Manufacturer: PANACEA BIOTEC

Rs 116.66 / TUBE
Rs 125.44
NISE GEL-30G

NISE GEL-30G 7% off

(1)

Manufacturer: DR. REDDY'S

Rs 102.37 / TUBE
Rs 110.08

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