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DOMADOL-50MG
(1X10)
TRAMADOL-50MG
ANALGESIC COMBINATION (OPOIDS)
TORRENT PHARMACEUTICAL
Product Details
Tramadol Hydrochloride
Action
Indications
Contraindications
Route/Dosage
Interactions
Lab Test Interferences
Adverse Reactions
PrecautionsPatient Care Considerations
Administration/Storage
Assessment/Interventions
Patient/Family Education
(TRAM-uh-dole HIGH-droe-KLOR-ide)UltramClass: Analgesic
Action Binds to certain opioid receptors and inhibits reuptake of norepinephrine and serotonin; exact mechanism of action unknown.
Indications Relief of moderate to moderately severe pain.
Contraindications Acute intoxication with alcohol, hypnotics, centrally acting analgesics, opioids or psychotropic agents.
Route/Dosage
ADULTS & CHILDREN ³ 16 YR: PO 50–100 mg every 4–6 hr; maximum daily dose 400 mg. ELDERLY PATIENTS > 75 YR: PO 50–100 mg every 4–6 hr, maximum daily dose 300 mg. RENAL IMPAIRMENT: CRU < 30 ML/MIN. PO 50–100 mg every 12 hr (maximum 200 mg/day). CIRRHOSIS: 50 mg every 12 hours (maximum 100 mg/day).
Interactions
Carbamazepine: May reduce serum tramadol levels, leading to decreased effectiveness. MAO inhibitors: Risk of seizures may be increased.
Lab Test Interferences None well documented.
Adverse Reactions
CV: Vasodilation. CNS: Dizziness/vertigo; headache; somnolence; stimulation; anxiety; confusion; oordination disturbances; euphoria; nervousness; sleep disorder; seizures. DERM: Pruritus; sweating; rash. EENT: Visual disturbances; dry mouth. GI: Nausea; diarrhea; constipation; vomiting; dyspepsia; abdominal pain; anorexia; latulence. GU: Urinary retention/frequency; menopausal symptoms; increased creatinine; roteinuria. HEMA: Decreased hemoglobin. HEPA: Elevated liver enzymes. OTHER: Asthenia; hypertonia.
Precautions
Pregnancy: Category C. Lactation: Excreted in breast milk. Children: Not recommended for children < 16 yr. Elderly: Patients > 75 yr-concentrations may be slightly elevated; may have less ability to tolerate adverse effects; use reduced dosage. Head trauma: Use with caution in patients with increased intracranial pressure or head trauma. Hepatic disease: Dosage adjustments may be required in patients with cirrhosis. Renal impairment: Dosage adjustments may be required. CNS depressants: Use with caution and in reduced dosage when administering to patients receiving CNS depressants. Opioid dependence: Not recommended for patients who are opioid-dependent; use caution when administering to patients who have recently received substantial amounts of opioids.
PATIENT CARE CONSIDERATIONS
Administration/Storage
- Can be taken without regard to meals.
- Administer medication before pain becomes severe.
- Store at room temperature, in a tightly closed container.
Assessment/Interventions
- Obtain patient history.
- Assess degree, location and characteristics of pain before administering.
- Assess vital signs before administering medication. If patient is hypotensive or dyspneic, notify physician before administering.
- Monitor I&O and check for urinary retention.
- Assess the effectiveness of the medication in relieving pain.
OVERDOSAGE: SIGNS & SYMPTOMS Respiratory depression, seizures, vomiting
Patient/Family Education
- Instruct patient to take the prescribed dose at the recommended intervals.
- Inform patient to check with his/her healthcare provider first before taking any over-the-counter or prescription medications, including analgesics.
- Have patient report any serious side effects to the healthcare provider.
- Advise patient not to wait until pain level is high to self-medicate, because drug will not be as effective.
- Advise patient to avoid taking alcohol or other CNS depressants (g, sleeping pills).
- Advise the patient that this medication may cause drowsiness and to use caution while driving or using heavy equipment or performing other tasks requiring mental alertness.
- Advise patient to notify the healthcare provider if the pain is not relieved by the medication at the prescribed dosage.
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David S. Tatro
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