Product Details

Therapeutic Class: 

• Antiglaucoma Preparations and Miotics

Latanoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a prostaglandin analogue that works by increasing the outflow of aqueous fluid from the eyes.

Mecanism of Action: Latanoprost is a prostaglandin F2a analogue. Specifically, Latanoprost is a prostanoid selective FP receptor agonist that is believed to reduce the intraocular pressure (IOP) by increasing the outflow of aqueous humor. Studies in animals and man suggest that the main mechanism of action is increased uveoscleral outflow. Elevated IOP represents a major risk factor for glaucomatous field loss. The higher the level of IOP, the greater the likelihood of optic nerve damage and visual field loss.

Dosing and Indication:

Adult: As 0.005% solution; Instill 1 drop every evening.

For the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.

Adverse Effects:

Common: Hives, difficult breathing; swelling of your face, lips, tongue, or throat.

• Increase in brown pigmentation of the iris.
• Blurred vision
• Burning and stinging
• Dry eye, Excessive tearing, Eye pain.
• Conjunctival hyperemia.

Drug Interaction:

• Acebutolol: Latanoprost may increase the hypotensive activities of Acebutolol.
• Acelofenac: The therapeutic efficacy of Latanoprost can be decreased when used in combination with Aceclofenac.

How should you use latanoprost ophthalmic

• Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
• The usual dose of latanoprost ophthalmic is 1 drop into the affected eye every evening. Follow your doctor's dosing instructions very carefully.
• Do not use while wearing soft contact lenses. A preservative in this medicine could permanently stain the lenses. Use the medicine at least 15 minutes before inserting your contact lenses.
• Wash your hands before using the eye drops.

To apply the eye drops:

• Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop.

• Close your eyes for 2 or 3 minutes with your head tipped down, without blinking or squinting. Gently press your finger to the inside corner of the eye for about 1 minute, to keep the liquid from draining into your tear duct.

• Wait at least 5 minutes before using any other eye drops your doctor has prescribed.